Novosibirsk State Pedagogical University Bulletin, 2013, vol. 3, no. 5, pp. 122–127
UDC: 
616.127-005.4

Antioxidant system of subcellular fraction of hepatocyts after experimental stroke

Ibragimov K. U. 1 (Tashkent, Republic of Uzbekistan)
1 Tashkent Pediatric Medical Institute
Abstract: 

It is studied antiperoxyde activity mitochondrial and microsomal fraction of hepatocytes in speaker experimental stroke. In microsomal of the fractions liver increase existed after ischemia-reperfution of brain antiperoxed activity and reduction to activities superoxyd dismutase, on background of the increase the contents malon dyaldehids and middle molekular peptide. In mitochondrial of the fractions liver activity ferment antiperoxyde of the system increased and was noted reduction of the ferment antiradical protection with most deflection before 6 hours after reperfution

Keywords: 

antioxidant system, mitochondria, microsomal fraction, stroke

For citation:
Ibragimov K. U. Antioxidant system of subcellular fraction of hepatocyts after experimental stroke. Novosibirsk State Pedagogical University Bulletin, 2013, vol. 3, no. 5, pp. 122–127.
References: 

1. Brusov O. S., Gerasimov A. I., Panchenko L. F. Influence natural ingibitors of radical reactions to autooxidation of adrenaline. Bulletin experimental biology and medicine, 1976, 87(1), pp. 33–35. (In Russian)
2. Gabrieljan N. I., Dmitriev A. A., Kulakov G. P., Mekikyan A. M., Shcerbaneva O. I. Diagnostic value of definition of average molecules in plasma of blood at nephrological diseases. Clinical medicine, 1981, vol. LIX, no. 10, pp. 38–42. (In Russian)
3. Ibragimov U. K., Haibullina Z. R. Apoptosis. The Manual. Tashkent, 2007, 81 p.
4. Koroljuk M. A., Ivanova L. I., Majorova I. G., Tokarev V. F. Method of definition
of katalas. Laboratory business, 1988, pp. 16–19.
5. Clinical children's neurology (ed.) A.S. Petruhina: the Management. Moscow: Publishing house Medicine, 2008. 1088 p. (In Russian)
6. Nagoev B. S., Tulupova M. V. Studying pro-oxidizer properties of plasma of blood
of psoriases. Clinical laboratory diagnostics, 2008, no. 8, pp. 15–17. (In Russian)
7. Pirs E. Histochemistry. Moscow, 1962. 648 p. (In Russian)
8. Materials ІІ the Russian international congress: Cebrovaskulyar pathology and an insult. 2010. (In Russian)
9. Ergashev J. D., Sigatullina M. I., Ibragimov U. K. Neuropsychic growth of children with hypoxi – ischemic encephalopathy. The 2th World Congress of Neonatology.-6th – 9th January, 2010, Luxor, Egypt. p.19.
10. Ibragimov U. K. Hypoxi-ishemic encephalopathy in children. The 2th World Congress of Neonatology. -6th – 9th January, 2010. Luxor, Egypt. p.18.
11. Muresanu D. F. Neurotrophic factors. Bucuresti: Libripress Publ., 2003. 268p.
12. Sloviter R. Apoptosis: a guide for perplexed. Trends Pharmacol Sci., 2002, vol. 23, pp. 19–24.

Date of the publication 26.10.2013