Novosibirsk State Pedagogical University Bulletin, 2013, vol. 3, no. 5, pp. 66–69
© Ibragimov K. U., 2013
UDC: 
616.052:616.003

Experimental stroke: different affect of treatment with antioxidant and antihypoxant drugs

Ibragimov K. U. 1 (Tashkent, Republic of Uzbekistan)
1 Tashkent Pediatric Medical Institute
Full text (Open Access) — Downloaded 2870
Abstract: 

As a result of cerebral ischemia in the mitochondria and the microsomal fraction of the liver significantly accumulated MDA, the activity of the enzymes catalase and SOD (superoxide dismutase) decreased. The use of antioxidant emoksipina and antihypoxant aktovegina led to a decrease in MDA in the MX and MC fractions of hepatocytes and restoration activities of the enzymes SOD and APA

Keywords: 

antioxidant, antihypoxant, stroke

For citation:
Ibragimov K. U. Experimental stroke: different affect of treatment with antioxidant and antihypoxant drugs. Novosibirsk State Pedagogical University Bulletin, 2013, vol. 3, no. 5, pp. 66–69.
References: 

1. Clinical children's neurology (ed.) A.S. Petruhina: the Management. Moscow: Publishing house Medicine, 2008. 1088 p. (In Russian)
2. Pirs E. Histology chemistry. Moscow, 1962. 648 p. (In Russian)
3. Brusov O.S., Gerasimov A.I., Panchenko L.F. Influence natural ingibitors of radical reactions to autooxidation of adrenaline. The bulletin experimental biology and medicine, 1976, no. 87 (1), pp. 33–35. (In Russian)
4. Gabrieljan N.I., Dmitriev A.A., Kulakov G.P., Mekikyan A.M., Shcerbaneva O.I. Diagnostic value of definition of average molecules in plasma of blood at nephrological diseases. Clinical medicine, 1981, vol. LIX, no. 10, pp. 38–42. (In Russian)
5. Ibragimov K.U., Haibullina Z.R. Condition mikrosomal and mitochondrial fractions of a liver at an experimental ischemia of a brain at rats. Bulletin RSМU. Journal of the All-Russia State medical university, 2009, no. 3, p. 243. (In Russian)
6. Koroljuk M.A., Ivanova L.I., Majorova I.G., Tokarev V.F. Method of definition of katalas. Laboratory business, 1988, pp. 16–19. (In Russian)
7. Nagoev B.S., Tulupova M.V. Studying pro-oxidizer properties of plasma of blood of psoriases. Clinical laboratory diagnostics, 2008, no. 8. pp. 15–17. (In Russian)
8. Hajbullina Z.R., Ibragimov U.K. Known molecular mechanisms neuron damages at hypoxias a brain of embryo. Medical journal of Uzbekistan, 2009, no. 2, pp. 64–72.
9. Hajbullina Z.R., Ibragimov U.K., Salihova S.R., Mufazdalov Sh. A. Reaction of cellular elements of blood on the general hypoxias of organism. The Pathology, Tashkent, 2010, no. 1, pp. 27–36.

Date of the publication 26.10.2013