Novosibirsk State Pedagogical University Bulletin, 2017, vol. 7, no. 2, pp. 50–69
© Panova A. S., Subotyalov M. A., 2017
UDC: 
57(091)

Development of scientific physiological school at Novosibirsk State Pedagogical University

Panova A. S. 1 (Novosibirsk, Russian Federation), Subotyalov M. A. 1 (Novosibirsk, Russian Federation)
1 Novosibirsk State Pedagogical University, Novosibirsk, Russian Federation
Full text (Open Access) — Downloaded 4501
Abstract: 

Introduction. The article is devoted to the review of the stages of formation and development of a scientific school on the basis of the Anatomy, Physiology and Safety of Life Department at Novosibirsk State Pedagogical University, which is one of the branches of the largest in the world I.P. Pavlov’s physiological school. The purpose of the article is to investigate the process of the formation of a scientific physiological school under the guidance of professor R.I. Aizman.
Materials and Methods. The authors employed the comparative-historical and analytic methods of historical-biological research.
Results. The results contain identification and presentation of a brief description of the prerequisites and main periods in the development of the scientific school. The authors identified four stages of the scientific school development: the background period, the period of formation, the period of development and the present period. The fundamental role of professor A.G. Ginetsinsky and professor L.K. Velikanova in the formation of the physiological school in Novosibirsk Pedagogical Institute is emphasized. The authors outlined the following key fields of the scientific school: the study of kidney function and water-salt metabolism (renal physiology); research of morphofunctional and psychophysiological basis of health of all participants of the educational process under the influence of various environmental factors; correction of homeostatic parameters of an organism in conditions of pathology and its experimental modeling. The main results of the long-term work of the school are presented. Within the framework of the first direction, the members of the scientific school have studied the formation of mechanisms of osmotic, ionic and volume homeostasis regulation in ontogeny and the development of their reliability; for the first time, all stages of water-salt metabolism regulation mechanisms of humans have been studied; the influence of various factors (environment, gender, type of body constitution, intake of substances) on the system state was established at normal and pathological conditions (diabetes mellitus, renal insufficiency) and methods for correcting disturbed homeostatic parameters were developed. On the second direction, the influence of individual typological and ethnic characteristics, as well as the learning conditions and the level of motor activity on the morphofunctional and psychophysiological parameters of the organism at different stages of ontogeny, have been studied. Within the framework of the third topic, the members of the research team showed the effect of various substances in the experimental modeling of disorders of carbohydrate metabolism, acute renal failure, and osteoporosis.
Conclusion. In conclusion, the authors confirm the correspondence of the scientific physiological school created under the leadership of R.I. Aizman, to all the criteria of a scientific school (the presence of a leader, the succession of generations, the unity of problems, the duration of existence in time and space, recognition of the contribution to science from other members of the disciplinary scientific community).

Keywords: 

History; biology; human physiology; school; kidneys; renal function; metabolism; safety

https://www.scopus.com/record/display.uri?src=s&origin=cto&ctoId=CTODS_1...

Development of scientific physiological school at Novosibirsk state pedagogical university

For citation:
Panova A. S., Subotyalov M. A. Development of scientific physiological school at Novosibirsk State Pedagogical University. Novosibirsk State Pedagogical University Bulletin, 2017, vol. 7, no. 2, pp. 50–69. DOI: http://dx.doi.org/10.15293/2226-3365.1702.04
References: 
  1. Aizman R., Brismar H., Celsi G. Nitric oxide inhibits potassium transport in the rat distal colon. American Journal of Physiology – Gastrointestinal and Liver Physiology. 1999, vol. 276, no. 1 39-1, pp. 146–154.
  2. Aizman R. I., Buduk-Ool L. K. S., Krasil’nikova V. A. Morphological, functional and psychological development of children living permanently in the Tuva republic. Alaska Medicine. 2007, vol. 49, no. 2, pp. 133–138.
  3. Aizman R. I., Golovin M. S., Girenko L. A. Age-specific features in renal response to food intakes and training loads in young professional skiers. Human Physiology. 2014, vol. 40, no. 4, pp. 450–455.
  4. Aizman R., Grahnquist L., Celsi G. Potassium homeostasis: ontogenetic aspects. Acta Paediatrica, International Journal of Paediatrics. 1998, vol. 87, no. 6, pp. 609–617. DOI: http://dx.doi.org/10.1080/080352598750013987
  5. Aizman R. I., Koroshchenko G. A., Gaidarova A. P., Lukanina S. N., Subotyalov M. A. The mechanisms of plant rhizome Curcuma longa action on carbohydrate metabolism in alloxan – induced diabetes mellitus rats. American Journal of Biomedical Research. 2015, vol. 3, no. 1, pp. 1–5.
  6. Aizman R. I., Koroshchenko G. A., Gaidarova A. P., Sakharov A. V., Subotyalov M. A. The mechanisms of Curcuma longa rhizome action on glucose metabolism in alloxan – induced diabetic rats. International Ayurvedic Medical Journal. 2014, vol. 2, no. 5, pp. 752–760.
  7. Aizman R. I., Rabinowitz L., Mayer-Harnisch C. Early effects of uninephrectomy on K homeostasis in unanesthetized rats. American Journal of Physiology – Regulatory Integrative and Comparative Physiology. 1996, vol. 270, no. 2 39-2, pp. R434–R442.
  8. Aizman R., Wang Z. M., Yasui M., Celsi G., Aperia A. Developmental changes of N/K-ATPase in rat colon. Pediatric Nephrology. 1994, vol. 8, no. 5, pp. 60.
  9. Aperia A., Cheng X. -J., Fisone G., Aizman O., Aizman R., Levenson R., Greengard P. PKA-mediated phosphorylation and inhibition of Na+-K+-ATPase in response to β-adrenergic hormone. American Journal of Physiology – Cell Physiology. 1997, vol. 273, no. 3 42-3, pp. 893–901.
  10. Celsi G., Kistner A., Aizman R., Eklöf A. Ch., Ceccatelli S., Santiago A. De., Jacobson S. H. Prenatal dexamethasone causes oligonehhronia, sodium retention, and higher blood pressure in the offspring. Pediatric Research. 1998, vol. 44, no. 3, pp. 317–322. DOI: http://dx.doi.org/10.1203/00006450-199809000-00009
  11. Chanchaeva E. A., Aizman R. I. Age-related changes in blood plasma antioxidant activity in population of the Southern Altai. Journal of Evolutionery Biochemistry and Physiology. 2012, vol. 48, no. 2, pp. 152–154. DOI: http://dx.doi.org/10.1134/S0022093012020041
  12. Chanchaeva E. A., Aizman R. I. Interethnic differences in biochemical adaptation of the population of Gornyi Altai. Human Physiology. 2014, vol. 40, no. 2, pp. 179–183. DOI: http://dx.doi.org/10.1134/S0362119714020054
  13. Chanchaeva E. A., Aizman R. I., Gerasev A. D. Contemporary perception of antioxidant system of human organism. Human Ecology. 2013, no. 7, pp. 50–58.
  14. Chanchaeva E. A., Aizman R. I., Sidorov S. S. Gender variability of morphofunctional indices in adolescents of mountain Altai. Gigiena i sanitariia. 2016, vol. 95, no. 3, pp. 269–273. DOI: http://dx.doi.org/10.18821/0016-9900-2016-95-3-269-273
  15. Chanchaeva E. A., Kogteva O. S., Aizman R. I. Antioxidant activity of blood plasma in Altai aborigines. Human physiology. 2012, vol. 38, no. 2, pp. 206–211. DOI: http://dx.doi.org/10.1134/S0362119712010069
  16. Garty H., Lindzen M., Scanzano R., Aizman R., Fuzesi M., Goldshleger R., Farman N., Blostein R., Karlish S. J. A functional interaction between CHIF and Na-K-ATPase: implication for regulation by FXYD proteins. American Journal of Physiology – Renal Physiology. 2002, vol. 283, no. 4, pp. 607–615. DOI: http://dx.doi.org/10.1152/ajprenal.00112.2002
  17. Gerasev A. D., Lukanina S. N., Koroshchenko G. A., Aizman R. I. Nutrition using natural zeolites for treatment of acute renal insufficiency. Peritoneal Dialysis International. 2001, vol. 21, no. S2, p. 35.
  18. Girenko L. A., Rubanovich V. B., Aizman R. I. Morphofunctional characteristics of 12- to 14-year-old boys as dependent on their physiological and chronological ages. Human Physiology. 2005, vol. 31, no. 3, pp. 346–351. DOI: http://dx.doi.org/10.1007/s10747-005-0055-7
  19. Golovin M. S., Aizman R. I. Audiovisual Stimulation Modulates Physical Performance and Biochemical and Hormonal Status of Athletes. Bulletin of Experimental Biology and Medicine. 2016, pp. 1–5. DOI: http://dx.doi.org/10.1007/s10517-016-3474-3
  20. Golovin M. S., Balioz N. V., Aizman R. I., Krivoshchekov S. G. Effect of audiovisual on the psychophysiological functions in track-and-field athletes. Human Physiology. 2015, vol. 41, no. 5, pp. 532–538. DOI: http://dx.doi.org/10.7868/S0131164615050045
  21. Krasil’nikova V. A., Buduk-Ool L. K., Aizman R. I. Morphofunctional development of tyvan and Russian schollchildren. Human Physiology. 2008, vol. 34, no. 1, pp. 66–72.
  22. Rabinowitz L., Aizman R. I. The central nervous system in potassium homeostasis. Frontiers in Neuroendocrinology. 1993, vol. 14, no. 1, pp. 1–26. DOI: http://dx.doi.org/10.1006/frne.1993.1001
  23.  Aizman R. I., Antonenko N. P., Velikanova L. K. Integration of mechanisms of regulation of water-salt balance during the growing water, salt and volume loads. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 1980, vol. 66, no. 9, pp. 1404–1411. (In Russian)
  24. Aizman R. I., Borisova S. A., Velikanova L. K., Nikitina N. F., Popov E. B. Features of renal function and water and electrolyte metabolism in children in the far North. HumanPhysiology. 1990, vol. 16, no. 4, pp. 115–119. (In Russian)
  25. Aizman R. I., Bystrushkin S. K., Sklyanov Yu. I. The water-salt metabolism during hyperhydration in different periods of pregnancy and its effect on the mother and foetus organisms. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 1992, vol. 78, no. 6, pp. 97–104. (In Russian)
  26. Aizman R. I., Velikanova L. K., Kalmykova N. E., Trofimovich E. M. Peculiarities of regulation of water-salt metabolism in children I and II period of childhood. Pediatrics. 1980, no. 2, pp. 35–37. (In Russian)
  27. Aizman R. I., Velikanova L. K., Pautova O. M. The effect of salt loading on water basins in the organism of rats from various age groups. Journal of Evolutionary Biochemistry and Physiology. 1986, vol. 22, no. 2, pp. 149–156. (In Russian)
  28. Aizman R. I., Golovin M. S., Girenko L. A. Psychophysiological characteristics of racing skiers and biathletes of different levels of sportsmanship. Theory and Practice of Physical Culture. 2013, no. 4, pp. 44–47. (In Russian)
  29. Aizman R. I., Kalmykova N. E., Borisova S. A., Slinkova I. P. Age peculiarities of water-salt metabolism in children and influence of certain environmental factors. Pediatrics. 1980, no. 2, pp. 13–27. (In Russian)
  30. Aizman R. I., Koroschenko G. A., Gaidarova A. P., Subotyalov M. A., Lukanina S. N., Sakharov A. V. Mechanisms of action of the powder of Curcuma longa rhizome plant on a carbohydrate metabolism at alloxan-induced diabetic rats. Bulletin of Siberian Medicine. 2014, vol. 13, no. 6, pp.105–112. (In Russian)
  31. Aizman R. I., Petrov O. N., Tupitsin, I. O. Age features of hemodynamics in man to stimulation of the osmoregulation system. Human Physiology. 1988, vol. 14, no. 4, pp. 647–651. (In Russian)
  32. Belichenko B. M., Grigorieva T. A., Shyyrapai U. V., Aizman R. I., Shoshenko K. A. Dynamics of organ blood flow in rats in postnatal ontogenesis. Journal of Evolutionary Biochemistry and Physiology. 2009, vol. 45, no. 2, pp. 246–251. (In Russian) DOI: http://dx.doi.org/10.1134/S0022093009020078
  33. Betekhtin M. S., Borodulin V. I., Pashkov K. A. The new Vienna medical school and its role in genesis of the Moscow and St. Petersburg dermatological schools. Problems of social hygiene, public health and history of medicine. 2014, no. 2, pp. 45–49. (In Russian)
  34. Borodulin V. I., Paleyev N. R., Topoliyanskiy A. V. About the cardiologic school of D. D. Pletniev: the revision of views. Problems of social hygiene, public health and history of medicine. 2013, no. 1, pp. 51–56. (In Russian)
  35. Borodulin V. I., Topoliyansky A. V. The scientific therapeutic school of A. N. Kryukov. Problems of social hygiene, public health and history of medicine. 2012, no. 5, pp. 57–61. (In Russian)
  36. Borodulin V. I., Topoliyansky A. V. V.D. Shervinskiy - L.E. Golubinin Therapeutic School at the Imperial Moscow University and USSR Department of Internal Medicine: M.P. Konchalovsky’s School. History of Medicine. 2015, vol. 2, no. 2, pp. 227–241. (In Russian) DOI: http://dx.doi.org/10.17720/2409-5583.t2.2.2015.17r
  37. Gerasev A. D., Lukanina S. N., Svyatash G. A., Panin L. E., Aizman R. I. Effect of natural zeolites on K transport in the rat gut. The Siberian Scientific Medical Journal. 2004, vol. 24, no. 2, pp. 88–90. (In Russian)
  38. Gerasev A. D., Koroshchenko G. A., Lukanina S. N., Taranov A. G., Aizman R. I. Effect of natural zeolites on renal functions and water-salt metabolism in rats. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 2003, vol. 89, no. 7, pp. 879–887. (In Russian)
  39. Gilinsky M. A., Aizman R. I., Koroshchenko G. A., Latysheva T. V., Novoselova T. I., Petrakova G. M., Sukhovershin R. A., Subotyalov M. A. Methylarginines in glycerol induced acute renal failure of rat. The Siberian Scientific Medical Journal. 2010, vol. 30, no. 4, pp. 82–86. (In Russian)
  40. Gliantsev S.P. Professor G.A. Orlov and his school. The 100th anniversary of birth. Surgery. Pirogov Journal. 2010, no. 4, pp. 79–80. (In Russian)
  41. Golovin M. S., Aizman R. I. The effect of audio-visual stimulation on autonomic regulation and  heart rate variability of athletes specializing in cyclic sports. Theory and Practice of Physical Culture. 2015, no. 1, pp. 19–22. (In Russian)
  42. Dmitrieva T. I., Aizman R. I., Kosolapov G. K., Peterson, V. D. Structural and functional state of the kidneys in children with dysmetabolic nephropathies. Pediatrics. Speransky Journal. 1990, vol. 69, no. 2, pp. 31–36. (In Russian)
  43. Elkova N. G., Aizman R. I. The development of water and salt homeostasis during normal and abnormal embryogenesis in rats. Journal of Evolutionary Biochemistry and Physiology. 1993, vol. 29, no. 5–6, pp. 487–494. (In Russian)
  44. Ershov K. I., Rusova T. V., Falameeva O. V., Sadovoy M. A., Aizman R. I., Kolosova N. G. Bone matrix glycosaminoglycans and osteoporosis development in early aging OXYS rats. Advances in Gerontology. 2011, vol. 1, no. 1, pp. 57–62. (In Russian) DOI: http://dx.doi.org/10.1134/S2079057011010061
  45. Koroshchenko G. A., Aizman R. I., Subotyalov M .A., Gajdarova A. P. Nephroprotective effect of herbal remedy Tejas on model acute renal failure. Plant Resources. 2014, vol. 50, no. 2, pp. 270–278. (In Russian)
  46. Koroshchenko G. A., Subotyalov M .A., Gerasev A. D., Aizman R. I. Influence of a rhizome of plant Curcuma longa on a carbohydrate balance in experiments on rats. The Siberian Scientific Medical Journal. 2011, vol. 31, no. 3, pp. 92–96. (In Russian)
  47. Kushner S. R., Iglina N. G., Aizman R. I. Effect of the water deprivation during pregnancy on the water-salt tissue composition and kidney function in the rat offspring of the first and second generation. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 2001, vol. 87, no. 9, pp. 1184–1192. (In Russian)
  48. Lebedev A. V., Subotyalov M. A., Aizman R. I. Sociotipičeskij portrait of the female students of the University, taking into account their psycho-physiological characteristics. The Bulletin of Kemerovo State University. 2011, no. 3 (47), pp. 154–159. (In Russian)
  49. Mikirtichan G. L.  Michael Maslov’s school. Issues of Modern Pediatrics. 2009, vol. 8, no. 1, pp. 150–154. (In Russian)
  50. Osadchuk L. V., Popova A. V., Tumanik O. V., Subotialov M. A., Aĭzman R. I. Androgens deficiency in men with overweight and obesity. Problems of Reproduction.  2012, no. 4, pp. 76–79. (In Russian)
  51. Petrova A. V., Iglina N. G., Sakharov A. V., Aizman R. I. Effect of dexamethasone on morphology and renal function in rats. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 2004, vol. 90, no. 8–2, pp. 68–69. (In Russian)
  52. Pirumova I. V., Subotyalov M. A., Aizman R. I. Psychophysiological characteristics of students of different constitutional types in traditional and single-sex education. Bulletin of Siberian Medicine. 2005, vol. 4, no. S1, p. 166. (In Russian)
  53. Rubanovich V. B., Aizman R. I. Morphofunctional development of adolescents depending on sexual maturity and type of physical activity. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 2004, vol. 90, no. 8–2, p. 420. (In Russian)
  54. Rubanovich V. B., Girenko L. A., Aizman R. I. Characteristics of the Morphofunctional Development of 7- to 14-Year-Old Boys with Different Types of Adaptive Response. Human Physiology. 2003, vol. 29, no. 3, pp. 48–53. (In Russian)
  55. Sazonova O. V, Trofimovich E. M., Korotcenko G. A., Ageeva T. A., Aizman R. I., Subotyalov M. A., Selivanova S. V. To question about integrated prevention of diabetes taking into account the man-made factors of environment (experimental results). Occupational Medicine and Industrial Ecology. 2012, no. 5, pp. 33–37. (In Russian)
  56. Finkinshtein Ya. D., Aizman R. I., Turner A. Ya., Pantyuchin I. V. Reflex mechanism of potassium homeostasis regulation. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 1973, vol. 59, no. 9, pp. 1429–1436. (In Russian)
  57. Finkinshtein Ya. D., Kogan A. S., Turner A. Ya., Aizman R. I. On liver osmoreceptor localization. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 1972, vol. 58, no. 5, pp. 722–728. (In Russian)
  58. Shyyrapai U. V., Belichenko V. M., Shoshenko С. A., Aizman R. I. The glomerular apparatus and renal blood flow in rats during postnatal ontogenesis. Neuroscience and Behavioral Physiology – Sechenov Physiology Journal. 2008, vol. 94, no. 4, pp. 456–464. (In Russian)
Date of the publication 30.04.2017