Novosibirsk State Pedagogical University Bulletin, 2016, vol. 6, no. 5, pp. 169–180
© Bedareva A. V., Zubrikova K. Y., Ganieva L. H., Litvinova N. A., 2016
UDC: 
57.02 + 57.04

Identifying individual olfactory sensibility to pheromonal and non-pheromonal stimuli

Bedareva A. V. 1 (Kemerovo, Russian Federation), Zubrikova K. Y. 1 (Kemerovo, Russian Federation), Ganieva L. H. 1 (Kemerovo, Russian Federation), Litvinova N. A. 1 (Kemerovo, Russian Federation)
1 Kemerovo State University, Kemerovo, Russian Federation
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Abstract: 

Olfactory analyzer and the vomeronasal organ are able to perceive pheromonal and/or non-pheromonal stimuli and they interact to perform chemosensory information-processing functions. However, the human perception of chemosignals depends on individual sensibility. If the threshold of sensibility for the male and female olfactory analyzer perceiving any non-pheromonal stimulus has been identified, the perception of pheromonal stimuli has not been properly studied. Therefore, the purpose of this article is to investigate individual sensibility to pheromonal and non-pheromonal stimuli of men and women at reproductive age. In present study we identified the threshold of sensibility to pheromonal and non-pheromonal stimuli of 40 females and 26 males aged 18-24 years old using the method described by T.Hammel and H.R.Briner. In this study we tested the females during two phases of menstrual cycle: receptive (the period of ovulation) and non-receptive. All recipients participating in the olfactory test perceived male (osmopherone) and female (osmopherine) pheromones in different concentration. It was found that individual olfactory sensibility influenced the perception of non-pheromonal stimuli, on the other hand, subjective perception of pheromones was associated with the vomeronasal organ. In our study each concentration of osmopherone and osnopherine was analysed as a separate odour that had different associations. During the perception of osmopherine the participants had the following associations: putrefactive odour (10 %), flowery odour (66 %) and fruity odour (24 %). As far as osmopherone is concerned, the most frequent associations were putrefactive odour (14 %), flowery odour (60 %) and woody odour (26 %). The females were more sensitive to male's pheromones than man to female’s ones. It could be explained by the idea that females need acute sense of smell in order to fulfill their reproductive and parental functions. It is especially significant during the period of ovulation and choosing a sexual partner.

Keywords: 

threshold of sensibility; pheromonal and non-pheromonal stimuli; osmopherone and osnopherin

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Identifying individual olfactory sensibility to pheromonal and non-pheromonal stimuli

For citation:
Bedareva A. V., Zubrikova K. Y., Ganieva L. H., Litvinova N. A. Identifying individual olfactory sensibility to pheromonal and non-pheromonal stimuli. Novosibirsk State Pedagogical University Bulletin, 2016, vol. 6, no. 5, pp. 169–180. DOI: http://dx.doi.org/10.15293/2226-3365.1605.12
References: 
  1. Moshkin M. P., Gerlinskaya L. A., Kolosova I. E., Litvinova N. A. et al. Change the smell of male students in the exam. Russian Journal of Physiology name of Sechenov. 2006, no. 10, pp. 1250–1259. (In Russian)
  2. Novikov S. N. Pheromones and reproduction of mammals. Leningrad, Nauka Publ., 1988, 168 p. (In Russian)
  3. Attems J., Walker L., Jellinger K. A. Olfaction and Aging: A Mini-Review. Gerontology. 2015, vol. 61, pp. 485–490. DOI: http://dx.doi.org/10.1159/000381619
  4. Grammer K., Fink B., Neave N. Human pheromones and sexual attraction. Eur. J. Obstet. Gynec. Reprod. Biol. 2005, vol. 118, pp. 135–142. DOI: http://dx.doi.org/10.1016/j.ejogrb.2004.08.010
  5. Hummel T., Kobal G., Gudziol H., Mackay-Sim A. Normative data for the ‘Sniffin sticks’ including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects.  Eur. Arch. Otorhinolaryngol. 2007, vol. 264, pp. 237–243. DOI: http://dx.doi.org/10.1007/s00405-006-0173-0
  6. Hummel T., Krone F., Lundström J. N., Bartsch O. Androstadienone odor thresholds in adolescents. Hormones and behavior. 2005, vol. 47, pp. 306–310. DOI: http://dx.doi.org/10.1016/j.yhbeh.2004.10.007
  7. Jacob T. J. C., Wang L., Jaffer S., McPhee S. Changes in the Odor Quality of Androstadienone during Exposure-Induced Sensitization. Chemical Senses. 2006, vol. 31, pp. 3–8. DOI: http://dx.doi.org/10.1093/chemse/bji073
  8. Kaeppler K., Mueller F. Odor classification: a review of factors influencing perception-based odor arrangements. Chem Senses. 2013, vol. 38, pp. 189–209. DOI: http://dx.doi.org/10.1093/chemse/bjs141
  9. Keller A., Vosshall L. B. Olfactory perception of chemically diverse molecules. BMC Neurosci. 2016, vol. 17, p. 55. DOI: http://dx.doi.org/10.1186/s12868-016-0287-2
  10. Mazzatenta A., Cellerino A., Origlia N., Barloscio D., Sartucci F., Di Giulio C., Domenici L. Olfactory phenotypic expression unveils human aging. Oncotarget. 2016, vol. 7, pp. 193–200. DOI: http://dx.doi.org/10.18632/oncotarget.8393
  11. Moshkin M. P., Litvinova N. A., Bedareva A. V., Bedarev M. S., Litvinova E. A., Gerlinskaya L. A. Odor as an Element of Subjective Assessment of Attractiveness of Young Males and Females. Journal of  Evolutionary Biochemistry and Physiology. 2011, vol. 47, pp. 62–72. DOI: http://dx.doi.org/10.1134/S0022093011010099
  12. Moshkin M., Litvinova N., Litvinova E. A., Bedareva A., Lutsyuk A., Gerlinskaya L. Scent Recognition of Infected Status in Humans. J Sex Med. 2012, vol. 9, pp. 3211–3218. DOI: http://dx.doi.org/10.1111/j.1743-6109.2011.02562.x
  13. Oliveira-Pinto A. V., Santos R. M., Coutinho R. A., Oliveira L. M., Santos G. B., Alho A. T. L., Leite R. E., Farfel J. M., Suemoto C. K., Grinberg L. T., Pasqualucci C. A., Jacob-Filho W., Lent R. Sexual Dimorphism in the Human Olfactory Bulb: Females Have More Neurons and Glial Cells than Males. PLoS ONE. 2014, vol. 9, e111733. DOI: http://dx.doi.org/10.1371/journal.pone.0111733
  14. Preti G., Wysocki C. J., Barnhari K. Т., Sondheimer S. J., and Leid J. J., Male Axillary Extracts Contain Pheromones that Affect Pulsatile Secretion of Luteinzing Hormone and Mood in Women Recipients. Biology Reproduct. 2003, vol. 68, pp. 2107–2113. DOI: http://dx.doi.org/10.1095/biolreprod.102.008268
  15. Savic I., Berglund H., Lindstrom P. Brain response to putative pheromones in homosexual men. Proc. Natl. Acad. Sci. USA. 2005, vol. 102, pp. 7356–7361. DOI: http://dx.doi.org/10.1073/pnas.0407998102
  16. Sheldon M. S., Cooper M. L., Geary D. C. et al. Fertility cycle patterns in motives for sexual sehavior. Pers. Soc. Psychol. Bull. 2006, vol. 32, pp. 1659–1673. DOI: http://dx.doi.org/10.1177/0146167206292690
  17. Secundo L., Snitz K., Weissler K., Pinchover L., Shoenfeld Y., Loewenthal R., Agmon-Levin N., Frumin I., Bar-Zvi D., Shushan S., Sobel N. Individual olfactory perception reveals meaningful nonolfactory genetic information. Proc Natl Acad Sci USA. 2015, vol. 112, pp. 8750–5. DOI: http://dx.doi.org/10.1073/pnas.1424826112
  18. Shinohara K., Morofushi M., Funabashi T. et al. Axillary pheromones modulate pulsatile LH secretion in humans. Neuroreport. 2001, vol. 12, pp. 893–895. DOI: http://dx.doi.org/10.1097/00001756-200104170-00005
  19. Tamagawa A., Gerlinskaya L. A., Nagatomi R., Moshkin M. P. Female Pheromone and Physical Exercise Improve Endocrine Status in Elderly Japanese Men. Anti-Aging Medicine. 2008, vol. 5, pp. 57–62. DOI: http://dx.doi.org/10.3793/jaam.5.57
  20. Vasuki A. K., Fenn T. K., Devi M. N., Hebzibah T. D., Jamuna M., Sundaram K. K. Fate and Development of Human Vomeronasal Organ – A Microscopic Fetal Study. J Clin Diagn Res. 2016, vol. 10, pp. 8–11. DOI: http://dx.doi.org/10.7860/JCDR/2016/15930.7373
Date of the publication 31.10.2016